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          • Frozen Hair Grinder
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          • DHFSTPRP-HR24
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          • Frozen Hair Grinder
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          • After cleaning and frozen grinding, hair samples are extracted using the methanol ultrasound method and detected using liquid chromatography-tandem mass spectrometry with multiple reaction monitoring
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                        DHFSTPRP-HR24 frozen hair grinder utilizes a special vertical up-and-down integrated vibration mode, which achieves the desired grinding effect quickly through the high-frequency reciprocating vibration, impact, and shear of grinding beads (zirconia, steel, glass, ceramic).
                    
          
                
          
            
          
        
          
    	
          
			
          
	
          
		
          
			
				
          
					
						Product Introduction
				
          
				
          
					
						DHFSTPRP-HR24 Frozen Hair Grinder utilizes a special vertical up-and-down integrated vibration mode, which achieves the desired grinding effect quickly through the high-frequency reciprocating vibration, impact, and shear of grinding beads (zirconia, steel, glass, ceramic). This results in samples that are more fully ground, more uniform, with better sample repeatability, and no cross-contamination between samples. Combined with the judicial appraisal technical specification SF/Z JD0107025-2018 "Liquid Chromatography-Tandem Mass Spectrometry Method for the Detection of 15 Drugs and Their Metabolites in Hair", it can quickly detect common drugs (such as heroin, methamphetamine, ketamine, ecstasy, marijuana) in hair on-site. The detection limits for various drugs have reached the requirements of the "Specifications for Hair Sample Testing of Drug-Involved Personnel" issued by the Ministry of Public Security. Since its launch, this product has been widely recognized in the industry and has received multiple innovations, as well as the acceptance report of the Key Laboratory of Toxicological Analysis of the Public Security Ministry of Beijing Public Security Bureau.
				
          
				
          
					
						This instrument is a recommended product in the judicial appraisal technical specification SF/Z JD0107025-2018 "Liquid Chromatography-Tandem Mass Spectrometry Method for the Detection of 15 Drugs and Their Metabolites in Hair".
				
          
			          
		
          
	
          
	
          
		
          
			
          
			
          
			
          
				
					
          
						
							Principle of the Product
					
          
					
          
						
							After cleaning and frozen grinding, hair samples are extracted using the methanol ultrasound method and detected using liquid chromatography-tandem mass spectrometry with multiple reaction monitoring (MRM) mode. Qualitative analysis is conducted by comparing the retention time, mass spectral characteristic fragment ion peaks, and relative abundance ratios of the ion pairs with those of the parallel blank samples and spiked samples for control purposes.
					
          
				          
			
          
		
          
		
          
			
          
				
          
				
          
				
          
					
						
          
							
								Product Features
						
          
						
          
							
								○ High efficiency grinding
          
								Simultaneously process 24 hair samples for rapid on-site grinding. The grinding equipment has a built-in program controller, making it easy to operate. It also provides feasible solutions for community drug rehabilitation and special personnel monitoring.          		
						
          
						
          
							
								○ Low-temperature grinding
          
								The temperature of the frozen grinding can be customized and adjusted to protect the components of the sample at low temperature and avoid destruction of the sample components.          		
						
          
						
          
							
								○ Professional grinding
          
								The instrument has completed nearly a thousand real sample tests in judicial centers and drug enforcement teams in Beijing, Ningbo, Sichuan, Hunan, Shanghai and other places. The positive detection rate is as high as 99%, effectively avoiding false positive interference caused by drug use.          		
						
          
					          
				
          
			
          
			
          
				
          
					
          
					
          
					
          
						
							
          
								
									Product Applications
							
          
							
          
								
									Sample for Grinding:
							
          
							
          
								
									1. Plant Tissues: roots, stems, leaves, flowers, fruits, seeds, etc.
							
          
							
          
								
									2. Animal Tissues: brain, heart, lung, stomach, liver, thymus, kidney, intestine, lymph nodes, muscle, bones, etc.
							
          
							
          
								
									3. Fungi and Bacteria: yeast, E. coli, etc.
							
          
							
          
								
									4. Food and Medicine: various food, pills, etc.
							
          
							
          
								
									5. Volatile Samples: coal, oil shale, wax products, etc.
							
          
							
          
								
									6. Plastics and Polymers: PE, PS, textiles, resins, etc.
							
          
							
          
								
									·Nucleic Acid/Protein Extraction
          
									Low-temperature grinding of samples can effectively inhibit nucleic acid degradation and preserve protein activity.          		
							
          
							
          
								
									·Analysis of Active Pharmaceutical Ingredients
          
									There are often significant differences between isomers of drug active ingredients. Low-temperature grinding can prevent molecular degradation due to pressure and heat.          		
							
          
							
          
								
									·Reducing Sample Volatility
          
									Low-temperature grinding can significantly reduce sample volatility and more completely retain the content of sample components.          		
							
          
							
          
								
									·Grinding Tough/Hard Samples
          
									For hard-to-grind samples such as tough plastics, high-strength plastics, and resins, low-temperature grinding can greatly improve grinding efficiency and effectiveness.          		
							
          
							
          
								
									homogenizer_tissuelyser
							
          
							
          
								
									DHFSTPRP-HR24 frozen hair grinder adopts a special vertical up-down integrated vibration mode, which achieves rapid grinding of samples through the high-frequency reciprocating vibration, impact, and shear of grinding beads (zirconia, steel, glass, ceramics). This results in more thorough and uniform grinding of samples, better sample reproducibility, and no cross-contamination between samples.
							
          
						          
					
          
				
          
				
          
					
          
						
          
						
          
						
          
							
								
          
									
										Forensic Appraisal Technical Specification SF/Z JD0107025-2018 "Liquid Chromatography-Tandem Mass Spectrometry Detection Method for 15 Drugs and Metabolites in Hair"
								
          
								
          
									
										1. Sample Preparation
								
          
								
          
									
										1.1 Case Sample
          
										The hair sample is washed twice with an appropriate amount of water and acetone by shaking, then dried and cut into approximately 1mm segments. The hair segments are then frozen and ground to a powder in a cryogenic grinder. Weigh 20mg of hair powder, add 1.0mL internal standard methoxamine standard working solution (methoxamine 1ng/mL), perform ice bath sonication for 30 minutes, centrifuge, transfer the supernatant, and dry at 60°C with air flow (or a dry nitrogen blower). The residue is re-dissolved with 100μL methanol for instrument analysis.          		
								
          
								
          
									
										1.2 Blank Sample
          
										Take 20mg of blank hair sample, add 1.0mL internal standard methoxamine standard working solution (methoxamine 1ng/mL), and follow the same extraction procedure as described in 6.1.1 for case samples.          		
								
          
								
          
									
										1.3 Spike Sample
          
										Take 20mg of blank hair sample, add the suspected target compound reference material that appears in the case sample, add 1.0mL internal standard methoxamine standard working solution (methoxamine 1ng/mL), and follow the same extraction procedure as described in 6.1.1 for case samples.          		
								
          
								
          
									
										homogenizer_tissuelyser
								
          
							          
						
          
					
          
					
          
						
          
							
          
							
          
							
          
								
									
          
										
											 
										
											 
									
          
									
          
										
											Multiple operation, good effect
										
											Highly efficient and fast operation can complete the grinding of 2x24, 2x48, 4x96 samples within 1 minute. It saves time and effort, and has small differences between batches and within batches. The extracted protein has a higher activity and longer nucleic acid fragments.
									
          
									
          
										
											No cross-contamination
										
											The sample tubes are in a fully enclosed state during the crushing process, and disposable centrifuge tubes and beads can be used. The samples are kept intact in the tubes, avoiding cross-contamination between samples and external contamination.
									
          
									
          
										
											Easy operation
										
											1. Built-in program controller, which can set parameters such as grinding time and vibration frequency of the rotor;
          
											2. User-friendly operating interface.          		
									
          
									
          
										
											Good stability
										
											1. Adopting vertical oscillation mode for more thorough grinding and better stability;
          
											2. During instrument operation, the noise is less than 55dB, which will not interfere with other experiments or instruments.          		
									
          
									
          
										
											Convenient for low-temperature operation
										
											When a low-temperature grinding environment is required, the adapter with the sample can be immersed in liquid nitrogen for 1-2 minutes, and then moved to the main unit for quick fixation to start grinding without the need for re-freezing, saving liquid nitrogen.
									
          
									
          
										
											Good repeatability
										
											Setting the same program for the same tissue sample can obtain the same grinding effect. The working time is short, and the sample temperature does not rise.
									
          
								          
							
          
						
          
						
          
							
          
								
          
								
          
								
          
									
										
          
											
												Technical Parameters
											
												 
										
          
										
          
											
												Application Fields:
											
												Hair grinding, tissue grinding, homogenization, cell lysis, material dispersion, preparation, sample mixing, oscillation, etc.
										
          
										
          
											
												Processing Capacity:
											
												Maximum processing capacity of 24 samples at the same time within 15 seconds, with built-in compressor for cooling
										
          
										
          
											
												Compatible Sample Tubes:
											
												24*(0.2-0.5mL) /24*2mL /6*(7-15)mL /2*25mL /2*50mL, and various specifications of grinding tubes can be customized
										
          
										
          
											
												Display:
											
												Touch screen display for convenient and intuitive operation
										
          
										
          
											
												Data Storage:
											
												Up to ten sets of experimental data can be stored, and different experimental samples are pre-set such as animal heart, spleen, lung, kidney, bone, skin, hair, etc.
										
          
										
          
											
												Cycle Mode:
											
												According to the set experimental parameters, the device can cycle through several pre-set parameter settings to further reduce human interference
										
          
										
          
											
												Anti-Vibration Principle:
											
												Innovative anti-vibration principle based on the German "schleifen-1" working mode, as well as the innovative three-dimensional motion of the grinding beads in the vertical, horizontal and rocking directions, to ensure maximum sample processing and instant crushing effect
										
          
										
          
											
												Maximum Feed Size:
											
												No specific requirements, can be adjusted according to the adapter
										
          
										
          
											
												Cooling function:
											
												Yes, adjustable from -30°C to 37°C
										
          
										
          
											
												Temperature control accuracy:
											
												+0.5°C
										
          
										
          
											
												Open lid operation protection:
											
												Electromagnetic lock
										
          
										
          
											
												Final particle size:
											
												~5µm
										
          
										
          
											
												Number of grinding platforms:
											
												(can accommodate number of grinding jars) > 2
										
          
										
          
											
												Fastening device:
											
												With automatic centering
										
          
										
          
											
												Homogenization speed:
											
												0-70 Hz/second, working time: 0 seconds to 99 minutes, user can set it
										
          
										
          
											
												Grinding ball diameter:
											
												0.1-30mm
										
          
										
          
											
												Grinding ball material:
											
												Alloy steel, chromium steel, zirconia, tungsten carbide, quartz sand
										
          
										
          
											
												Acceleration:
											
												Reaches maximum speed within 2 seconds
										
          
										
          
											
												Deceleration:
											
												Reaches lowest speed within 2 seconds
										
          
										
          
											
												Noise level:
											
												<55db
										
          
										
          
											
												Grinding mode:
											
												Wet grinding, dry grinding, and low temperature grinding are all available
										
          
										
          
											
												Temperature control can be additionally equipped:
											
												Has the ability to upgrade to ultra-low temperature liquid nitrogen refrigeration or air refrigeration
										
          
										
          
											
												Adapter material:
											
												Polytetrafluoroethylene, alloy steel
										
          
										
          
											
												Safety instructions:
											
												Fastening device with automatic centering, safety lock during operation, full protection
										
          
										
          
											
												Grinding kit material:
											
												Hard alloy, polytetrafluoroethylene (PTFE), zirconia
										
          
										
          
											
												Dimensions:
											
												630*300*480mm
										
          
										
          
											
												Weight:
											
												58 kg
										
          
									          
								
          
							
          
							
          
								
          
									
          
									
          
									
          
										
											
          
												
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													Frozen Hair Grinder DHFSTPRP-HR24
												
													homogenizer
												
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														Rapid hair grinding instrument
													
														DHFSTPRP-HP24
												
          
												
          
													
														Frozen Hair Grinder
													
														DHFSTPRP-HR24
												
          
												
          
													
														portable rapid hair grinder
													
														DH-2019
												
          
											          
										
          
									
          
								
          
							
          
						
          
					
          
				
          
			
          
		
          
	
          

          

        
          
    	
          
			
          
	Product List

          
            
            
			
          
            	
          
                    
          
                        
          
                	        DHFSTPRP-HR24
                            Unit
                        
          
                        
                            
          
                	            Host Machine
                                Unit
                            
          
                            
                            
          
                	            Adapters
                                set
                            
          
                            
                            
          
                	            Cooling Adapter
                                Set
                            
          
                            
                            
          
                	            Zirconia Grinding Bead No.5
                                Piece
                            
          
                            
                            
          
                	            Zirconia Grinding Bead No.3
                                Piece
                            
          
                            
                            
          
                	            Special Grinding Tube
                                Piece
                            
          
                            
                            
          
                	            Special Bead Loading Gun
                                Set
                            
          
                            
                    
          
                
          
                
          
                	
                    
                    
          
                        
          
                            
          
                                
                                    
                                        
          
                                            
          Description
          
                                            
          1
          ?2ml,1（2 in 1）
          ?2or?1.5ml,1（2 in 1）
          1000（2 in 1）
          1000（2 in 1）
          200
          1（Optional）
          
                                        
          
                                              		
                                    
                            
          
                        
          
                    
          
                
          
            
          
            
        
          
    
          
    





          

          

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